Biography
Prof. Dr. Clara Viñas Teixidor graduated in Chemistry at the Universitat Autònoma de Barcelona and later in Pharmacy at the Universitat de Barcelona. She worked as a pre-doctoral student at the Prof. Rudolph’s laboratory at The University of Michigan for a year. She is a Research Professor at the Institut de Ciència de Materials de Barcelona that belongs to the Spanish Council for Scientific Research since 2006. Previously, she worked in an industry dedicated to recovery of industrial residual waters, and at public institution involved in food science analysis as well as environmental control.
Her fields of research involve synthesis and derivatisation of boron clusters to be applied in medicine and biosensors, among others.
PAQ-Collabora Project
Development of New kit for Latent Fingerprint detection and Authentication "KIDAEM"
PAQ-Collabora Project
Development of New kit for Latent Fingerprint detection and Authentication "KIDAEM"
PAQ-Collabora Project
Development of New kit for Latent Fingerprint detection and Authentication "KIDAEM"
PROJECT PARTNERS
GEOGLOB-Lab Faculty of Sciences of Sfax
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LATIS-Lab National School of Engineers of Sousse
CEM-Lab National School of Engineers of Sfax
SOGIMEL Private Company
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PROJECT PARTNERS
GEOGLOB-Lab Faculty of Sciences of Sfax
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LATIS-Lab National School of Engineers of Sousse
CEM-Lab National School of Engineers of Sfax
SOGIMEL Private Company
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RESUME
RESUME
Registration
PROJECT NEWS
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04/04/2019 Call for POSTDOC recrutment
30/03/2019 Signature of the financial support memorandum by the minister of HER
22/03/2019 Coaching session @ Ministry
01/03/2019 First meeting of project members
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Professor Clara Vinas Plenary Speaker
Biography
Prof. Dr. Clara Viñas Teixidor graduated in Chemistry at the Universitat Autònoma de Barcelona and later in Pharmacy at the Universitat de Barcelona. She worked as a pre-doctoral student at the Prof. Rudolph’s laboratory at The University of Michigan for a year. She is a Research Professor at the Institut de Ciència de Materials de Barcelona that belongs to the Spanish Council for Scientific Research since 2006. Previously, she worked in an industry dedicated to recovery of industrial residual waters, and at public institution involved in food science analysis as well as environmental control.
Her fields of research involve synthesis and derivatisation of boron clusters to be applied in medicine and biosensors, among others.
Abstract
PURELY INORGANIC NANOMATERIALS: NEW OPPORTUNITIES OF BORON CLUSTERS IN MEDICINE
Clara Viñas
Institut de Ciència de Materials de Barcelona (ICMAB-CSICclara@icmab.es
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Relative to carbon, very little is currently known about boron in therapeutics. The aim of this presentation is to show the ability of boron clusters in producing new molecules for their desired application in nanomaterials and nanomedicine. In this regard, a new type of gold NPs, which is hydrophobic and completely insoluble in water when uncharged, but, when offered electrons by a suitable reducing agent, transfers readily to an aqueous.1 The design of water-soluble boron rich particles or macromolecules is of significance for medicine and for drug delivery. In addition, [3,3’-Co(1,2-C2B9H11)2]- has also been shown to form small monolayer nano-vesicles and micelles or lamellas in water depending on the concentration while.2 Both boron-rich metallacarboranes have shown to cross through synthetic lipid membranes and to accumulate within living cells, where they can be detected by B-H Raman Microspectroscopy.3 These results reveal unexpected properties at the interface of biological and synthetic membranes and demonstrate an alternative method for cell labelling and detection.4 The incorporation of hollow spherical carboranes as capping agents for magnetite/maghemite NPs5 and the interaction between metallabis-(dicarbollide) with proteins 6 and double-stranded DNA as well as “in vitro” and “in vivo” studies will be presented.7 The Kinase-Inhibitors-Loaded Boron Cluster as Hybrid Agents for Glioma-Cell-Targeting Therapy will be also presented.8
1 A. M. Cioran, A. D. Musteti, F. Teixidor, Z. Krpetic, I. A. Prior, Q. He, C. J. Kiely, M. Brust, C. Viñas, J. Am. Chem.Soc. 2012, 134, 212.
2 a) P. Bauduin, S. Prevost, P. Farràs, F. Teixidor, O. Diat, T. Zemb, Angew Chem Int Ed Engl. 2011, 50, 5298. b) D. Brusselle, P. Bauduin, L. Girard, A. Zaulet, C. Viñas, F. Teixidor, I. Ly, O. Diat, Angew. Chem. Int. Ed. 2013, 52, 12114.
3 M. Tarrés, E. Canetta, C. Viñas, F. Teixidor, A.J. Harwood, Chem. Commun, 2014, 50, 3370.
4 C. Verdiá-Báguena, A. Alcaraz, V. M. Aguilella, A.M. Cioran, S. Tachikawa, H. Nakamura, F. Teixidor, C. Viñas, Chem. Commun, 2014, 50, 6700.
5 a) E. Oleshkevich, A. Rosell, F. Teixidor, C. Viñas, Inorg. Chem., 2018, 57, 462. b) E. Oleshkevich, A. Rosell, A. Morancho, K. Galenkamp, J. Comella F. Teixidor, C. Viñas, Nanomedicine: Nanotechnology, Biology and Medicine, 2019, 20, 101986.
6 I. Fuentes, J. Pujols, C. Viñas, S. Ventura, F. Teixidor, Chem. Eur. J., 2019, 25, 12820 – 12829.
7 I. Fuentes, T. García-Mendiola, S. Sato, M. Pita, H. Nakamura, E. Lorenzo, F. Teixidor, F. Marques, C. Viñas, Chem. Eur. J., 2018, 24, 17239 – 17254.
8 a) M. Couto, I. Mastandrea, M. Cabrera, P. Cabral, F. Teixidor, H. Cerecetto, C. Viñas, Chem. Eur. J. 2017, 23, 9233 – 9238. b) M. Couto, M.F. García, C. Alamjn, M. Cabrera, P. Cabral, A. Merlino, F. Teixidor, H. Cerecetto, C. Viñas, Chem. Eur. J. 2018, 24, 3122 – 3126.
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